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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXN
All Species:
24.55
Human Site:
T236
Identified Species:
45
UniProt:
P49023
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49023
NP_001074324.1
591
64533
T236
P
S
P
V
P
A
I
T
V
N
Q
G
E
M
S
Chimpanzee
Pan troglodytes
XP_001159942
589
64154
T234
P
S
P
V
P
A
I
T
V
N
Q
G
E
M
S
Rhesus Macaque
Macaca mulatta
XP_001085795
563
61555
T242
P
S
P
V
P
A
I
T
V
N
Q
G
E
M
S
Dog
Lupus familis
XP_543425
664
72715
T247
P
S
P
V
P
A
I
T
V
N
Q
G
E
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI36
591
64458
T236
P
S
P
V
P
A
I
T
V
N
Q
G
E
M
S
Rat
Rattus norvegicus
Q66H76
586
64001
M227
G
G
K
A
G
P
L
M
K
E
K
P
K
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49024
559
61224
T237
P
S
P
V
P
A
I
T
V
S
Q
G
E
V
S
Frog
Xenopus laevis
Q2TCH4
506
55983
A197
V
P
K
D
L
E
D
A
P
T
P
K
S
F
K
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
S110
P
K
Y
S
F
A
P
S
T
A
I
N
K
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523601
581
64668
I224
V
G
T
V
E
E
Q
I
V
Q
Q
K
D
S
Y
Honey Bee
Apis mellifera
XP_624308
559
62451
K221
S
E
F
K
P
V
C
K
L
I
S
A
N
R
H
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
V104
P
V
Y
S
R
P
S
V
Q
S
L
L
S
Q
V
Sea Urchin
Strong. purpuratus
XP_780574
695
76058
M319
Q
Q
P
M
S
R
V
M
T
N
S
T
H
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
83.1
N.A.
93.7
74.9
N.A.
N.A.
84.7
41.2
21.6
N.A.
43.1
43.3
33.8
43.4
Protein Similarity:
100
99.1
92.8
85.2
N.A.
95.7
78.3
N.A.
N.A.
88.4
54.3
36.5
N.A.
54.8
57
47
56.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
86.6
0
20
N.A.
20
6.6
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
100
0
40
N.A.
26.6
13.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
54
0
8
0
8
0
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
0
8
0
0
8
16
0
0
0
8
0
0
47
0
0
% E
% Phe:
0
0
8
0
8
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
16
0
0
8
0
0
0
0
0
0
47
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
0
47
8
0
8
8
0
0
0
0
% I
% Lys:
0
8
16
8
0
0
0
8
8
0
8
16
16
0
8
% K
% Leu:
0
0
0
0
8
0
8
0
8
0
8
8
0
0
0
% L
% Met:
0
0
0
8
0
0
0
16
0
0
0
0
0
47
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
47
0
8
8
0
8
% N
% Pro:
62
8
54
0
54
16
8
0
8
0
8
8
0
0
8
% P
% Gln:
8
8
0
0
0
0
8
0
8
8
54
0
0
8
0
% Q
% Arg:
0
0
0
0
8
8
0
0
0
0
0
0
0
16
0
% R
% Ser:
8
47
0
16
8
0
8
8
0
16
16
0
16
8
47
% S
% Thr:
0
0
8
0
0
0
0
47
16
8
0
8
0
0
0
% T
% Val:
16
8
0
54
0
8
8
8
54
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _